In the heart of the Sierra Norte of Oaxaca, there is a small town where the West Sierra Madre joins the Easter Sierra Madre, also known as "Mixtec knot".

The Sierra Norte, known as La Sierra Juarez, is a mountain range that runs parallel to the Gulf of Mexico, from the State of Nuevo Leon and as it narrows forms the waist of the nation in Oaxaca, almost joins with the Sierra Sur, mountain chain which runs down from Alaska parallel to the Pacific Ocean and in Oaxaca is called "Mixtec knot".

The San Pablo Academic and Cultural Center is located in the heart of the historic center of the city of Oaxaca in what was part of the former convent of San Pablo, colonial building which dates from the 16th century, but by the telluric movements constantly wagging Oaxaca has had many modifications.

The purpose of the Cultural Center is "valuing the multicultural, mostly indigenous, heritage of Oaxaca and Mexico".

In the heart of the mountains of Oaxaca, it is one of the most significant populations of the state, in terms of music and culture. Pulsating center of the most intimate affairs of Mixe peoples mixes and holder of the heritage and tradition.